Postdoctoral Researcher in RNA 3D structure modeling

Deadline for applications: September 15th, 2025. Preferred job starting date: October 1st, 2025 or as soon as possible.

As a Postdoctoral Researcher, you will be involved in interdisciplinary analyses of RNA structure focused on mechanistic, structure-level understanding of how posttranscriptional modifications influence RNA folding and its ability to form alternative 3D structures.

This position is ideal for you if you have solid experience in bioinformatics and computational biology, in particular in simulations of RNA folding in 3D using coarse-grained models, Monte Carlo sampling and statistical potentials. We are also interested in applications from candidates with experience in software development, who can contribute to be our interdisciplinary work on RNA structure.

Our laboratory http://iimcb.genesilico.pl studies the structures and mechanisms of biological macromolecules, in particular RNA and macromolecular complexes involving nucleic acids, proteins, and small molecules. We use experimental approaches such as chemical probing, crystallography, cryo-EM, circular dichroism, and SAXS to characterize the structures and functions of RNAs and their complexes. We also develop and use computer programs for data analyses, in particular for modeling based on experimental data.

The Institute www.iimcb.gov.pl is equipped with state-of-the-art technology, has excellent core facilities and supportive administration. IIMCB benefits from numerous generous funding schemes for basic research through grants from international and national sources. The institute is located in a large biomedical campus that offers access to equipment and various possibilities of training and collaboration. We provide opportunities for interdisciplinary collaborations. The working language of the institute is English.

We offer:

• Full-time contract (“umowa o pracę”) for 8 months, with an intended extension depending on performance and applications for extramural funding.
• Gross monthly remuneration starting at 7500 PLN/month, net approx. 6000 PLN/month, commensurate with experience (the final monthly gross salary will be calculated individually during the employment process, taking into account the length of service). Additional bonuses such as the 13th salary after working for the Institute for six months in a given calendar year, or Christmas bonus may supplement this salary.
• Benefits including reduced-rate for an individual medical care package and membership in the MultiSport program
• Work in a multidisciplinary, international team, in a dynamic organization, with multiple opportunities for professional development, participation in courses, scientific training and academic mentoring
• Administrative and organizational support from professional English-speaking personnel

We require:

• Ph.D. in any relevant area (e.g., biology, computer science, etc.), defended no more than 7 years before the start of the contract (according to the rules of the funding agency).
• Fulfillment of formal criteria of the competition in particular section 2.1.1: https://tinyurl.com/5em5kbah
• Experience in all the following areas: 1. RNA structural bioinformatics, in particular molecular modeling,
  2. computational simulations of RNA and protein structure and dynamics, 3. programming in C/C++ and Python, and 4. development of potentials for scoring inter- and intra-molecular interactions in molecular models
• Proactive approach to achieving objectives, good interpersonal skills, collaborative and adaptive attitude
• Very good organizational skills, especially project and time management skills
• Very good command of English (written and oral communication) and presentation skills

Selection criteria:

Applications will be evaluated based on the following criteria:

How to apply:

• Apply via the recruitment system: https://system.erecruiter.pl/FormTemplates/RecruitmentForm.aspx?WebID=3e52d083a5fa4fdc8ee22cc075c47858
• In the subject of the message include "IIMCB-postdoc-RNA-3D-modeling" and your first and last name
• Your application must be submitted in English and should contain: 1) a CV including a publication list, 2) a cover letter including a short description of your key achievements and expertise in the four areas listed in this advertisement, 3) contacts to at least two potential referees, including your Ph.D. supervisor. At this stage, please do not attach copies of diplomas, etc.
• Please include the following statement in your CV: “I hereby agree to the processing of my personal data, included in the application documents by the International Institute of Molecular and Cell Biology in Warsaw, 4 Księcia Trojdena Street, 02-109 Warsaw, for the purpose of carrying out the current recruitment process.” Your personal data will be processed for the purpose of the recruitment procedure by the International Institute of Molecular and Cell Biology in Warsaw. Full information is available under the link https://tinyurl.com/2eawcm2x.
• Procedure for reporting irregularities, taking follow-up actions, and protecting whistleblowers: https://shorturl.at/u2mww
• We will contact only selected best candidates, who may be given additional questions and tasks as a part of the recruitment process

The Postdoctoral Researcher will be selected from candidates in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy https://tinyurl.com/54meyr6r. The competition may be extended or repeated until suitable candidates who fulfill all requirements are found.

This position is offered within a project entitled “Unraveling the influence of posttranscriptional modifications on RNA 3D structure formation and its dynamics, with the integrated use of theoretical and experimental approaches” carried out as the OPUS grant of the Polish National Science Centre (UMO-2020/37/B/NZ2/02456).

Benefits: